Methotrexate Safety Checklist! Methotrexate is a powerful DMARD, but safe prescribing requires a strict protocol. Before you write your next prescription, are you following these essential steps? 1. Pre-Treatment Screening (Baseline): Rule out any active infections. Get baseline CBC, LFT, and RFT. 2. Initiating Therapy: Always start with a low test dose (e.g., 5mg) for the first week. Re-evaluate the patient after one week for any immediate side effects before escalating the dose. 3. Monitoring

Dr. Makarov touches on the recent question of if Methotrexate negatively impacts egg quality! 🥚 Methotrexate is given when a patient has a confirmed ectopic pregnancy. An ectopic pregnancy is when embryo sticks to the outside of the womb, usually in the fallopian tubes, and begins to grow. Ectopic pregnancies are dangerous to the mother and are not viable. 🙅🤰 Studies have shown that Methotrexate is not directly connected to a decline in egg quality. Once the ectopic pregnancy is resolved, it