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6:39
technologynetworks.com
Complement System Made Easy- Immunology- Classical Alternate & Lectin pathway
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's plasma membrane.
Sep 7, 2018
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Code HAVIC @medschoolbro = Mystery Discount Complement System: 30-sec Review 🛣 Three pathways lead to complement activation: • Classical pathway activated by IgG or IgM • Alternative pathway activated by microbial surfaces • Lectin pathway activated by mannose on microbes 🌀 C3 convertase produces C3a and C3b. 🔥 C5 convertase produces C5a and C5b. 💥 MAC (C5b–C9) forms pores that destroy microbes, especially Neisseria. 🔑 Key functions: • C3a and C5a trigger mast cell degranulation • C5a direc
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