Sperm motility is a key measure of sperm quality, referring to the ability of sperm to move efficiently and progressively—essential for fertilizing an egg. When using donor sperm, motility is quantified What Does MOT Mean? MOT stands for "Motile Total" and indicates the number of progressively motile (actively swimming forward) sperm cells per milliliter in a donor sperm sample. The number following MOT (e.g., MOT20) refers to the millions of motile sperm per milliliter. For example: MOT5: 5 mil