Behavioral assays linked these molecular disturbances to functional outcomes. Exposed fish displayed increased locomotor activity, heightened anxiety-like behavior, and altered learning performance, ...

This study proposes a cross-species transcriptomic framework to predict vaccine reactogenicity, with implications for preclinical vaccine safety assessment. The findings show that mouse muscle ...

In a syngeneic CT26 model, murine STC-1010 significantly inhibits tumor growth and extends survival by 40%. New mechanistic datas reveal expansion of CD4 and CD8 T cells in draining lymph nodes ...

A new spatial transcriptomic technology captures RNA patterns without requiring expensive imaging ...

Testicular germ cell tumors (TGCTs) represent a unique clinical challenge due to their histological heterogeneity and varying responses to systemic therapy. While the majority of TGCTs are highly ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models often fail to fully recapitulate all aspects of the human disease. A ...

Toward the goal of elucidating endocrine system aging mechanisms, this study establishes the first single-cell aging atlas across multiple endocrine organs. The research reveals conserved aging ...

Abstract: Cardiovascular diseases (CVDs) and pathologies are often driven by changes in molecular signaling and communication, as well as in cellular and tissue components, particularly those ...

Aquaculture Department, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China Key Laboratory of Breeding and Reproductive Cultivation of Chinese ...

This session, part of the Statistical analysis in systematic reviews series, gave a short, non-technical, introduction to meta-analysis, which is the statistical method used for combining results ...

1 Department of Critical Care Medicine, The Brain Hospital of Guangxi Zhuang Autonomous Region, Liuzhou, China. 2 Department of Respiratory Medicine, The Chest Hospital of Guangxi Zhuang Autonomous ...