BMJ Open

Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study ...

Introduction Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by Onchocerca volvulus affecting millions predominantly in sub-Saharan Africa. Robust epidemiological ...

Bruker Announces Major Advancements at AGBT to Enable Complete High-Fidelity Spatial Biology Across the Biological Spectrum

Bruker Corporation (Nasdaq: BRKR) announced today significant portfolio advancements from Bruker Spatial Biology to be unveiled at the 2026 Advances in Genome Biology and Technology (AGBT) General ...
PharmiWeb

Parse Biosciences Launches Evercode Whole Transcriptome V4 With Shorter Workflow, Higher Sensitivity and Higher Cell Recovery

New chemistry reduces barriers to scaling single-cell studies across research settingsLaunch planned for March 2026, available across Evercode Whole Transcriptome product lineSEATTLE, Wash. & VENLO, ...
gut.bmj

Comprehensive single-cell analysis deciphered microenvironmental dynamics and immune regulator olfactomedin 4 in pathogenesis of gallbladder cancer

Objective Elucidating complex ecosystems and molecular features of gallbladder cancer (GBC) and benign gallbladder diseases is pivotal to proactive cancer prevention and optimal therapeutic ...
Phys.org

Scientists transform enigmatic cell structures into devices for recording RNA activity

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and the molecular events within them are dynamic, and developmental processes, ...
C&EN

Design, Synthesis, and Anti-Hepatocellular Carcinoma Evaluation Revealed by Transcriptome Analysis of Epimeric Sesquiterpene Lactones: Trilobolide-6-O-isobutyrate Analogues

Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou 571126, Hainan, People’s Republic of China Key Laboratory of Tropical Medicinal Plant ...
C&EN

Integrative Physiology, Transcriptome, and Metabolome Analysis Reveals Pathways and the Key Gene ZmARF27 Involved in Vigor Loss during Artificial Aging of Maize Seeds

Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold Land of ...
ascopubs.org

Clinical utility of comprehensive transcriptome testing in advanced solid tumors.

Evaluation of 68Ga-FAPI PET/CT and 18F-FDG PET/CT for the primary staging of non-small cell lung cancer (NSCLC). Application of an epigenomic-based classifier to identify cancer signal of origin on ...
Baylor College of Medicine

Baylor researchers develop and validate clinical diagnostic RNA sequencing test

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...
Frontiers

Correlating gene expression levels with transcription factor binding sites facilitates identification of key transcription factors from transcriptome data

Identification of key transcription factors from transcriptome data by correlating gene expression levels with transcription factor binding sites is important for transcriptome data analysis. In a ...