Background Tuberous sclerosis complex (TSC) is a genetic disease characterised by the growth of benign tumours. The Tuberous sclerosis Associated Neuropsychiatric Disorders (TAND) Checklist is used to ...

Background Network-based measures are emerging MRI markers in multiple sclerosis (MS). We aimed to identify networks of white (WM) and grey matter (GM) damage that predict disability progression and ...

The dazzling 36-month clinical data announced by uniQure (NASDAQ: QURE) showing a significant slowing of Huntington’s disease (HD) progression in patients treated with its gene therapy candidate ...

~ Pivotal study met primary endpoint; high-dose AMT-130 demonstrated statistically significant 75% disease slowing at 36 months as measured by cUHDRS compared to a propensity score-matched external ...

Credit: Getty Images Researchers identified clinical and magnetic resonance imagining predictors of fatigue worsening in patients with multiple sclerosis. Worsening fatigue in patients with multiple ...

This important manuscript presents a novel application of the SANDI (Soma and Neurite Density Imaging) model to study microstructural alterations in the basal ganglia of individuals with Huntington's ...

Having better physical performance is associated with higher cognitive function in people with multiple sclerosis (MS), particularly among those with more disability, a study finds. Disability levels, ...

Improved HDL-C metrics were associated with better scores on cognitive performance tests at midlife among women. Improved serum high-density lipoprotein (HDL) metrics during midlife are associated ...

Poststroke cognitive impairment can significantly impact functional outcomes and quality of life. While comprehensive neuropsychological evaluations are valuable in characterizing this impairment, ...

SAN DIEGO — The investigational drug pridopidine has demonstrated consistent, sustained, and clinically meaningful improvements in function, cognition, and fine motor skills in patients with ...

COGNITIVE decline in relapsing-remitting multiple sclerosis (RRMS) can progress independently of both relapses and MRI-detected disease activity, challenging traditional methods of monitoring MS ...

Credit: Getty Images In an interim analysis of ENLIGHTEN, researchers described changes in cognitive function over 1 year in patients with MS. For the Symbol Digit Modalities Test, clinically ...