How RNA binding selectivity arises from disordered regions

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...
Phys.org

Scientists transform enigmatic cell structures into devices for recording RNA activity

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and the molecular events within them are dynamic, and developmental processes, ...
News Medical

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
BioSpace

Mission Bio Announces Single-Cell Targeted DNA + RNA Assay at ASH 2025, Closing the Mutation-to-Expression Gap in Cancer Research

New Tapestri® assay measures both genotypic and transcriptional signals within individual cells, enabling researchers to map resistance, relapse, and lineage evolution across hematologic malignancies.
IEEE

scGCRC: Graph and Contrastive-Based Representation Learning for Single-Cell RNA-Seq Data Clustering

Abstract: The advent of single-cell RNA-sequencing (scRNA-seq) technology promotes biological analysis at the cellular level. Clustering cells to identify the type of cell is an important step in ...
News Medical

Comprehensive RNA analysis in single cells with short-read sequencing

This article and associated images are based on a poster originally authored by Marisa Amato and presented at ELRIG Drug Discovery 2025 in affiliation with Singleron Biotechnologies GmbH. This poster ...
EurekAlert!

New review decodes transcriptomics: bulk vs. single-cell RNA sequencing

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
SciTech Daily

New Tool Reads DNA and RNA in a Single Cell, Unlocking Secrets of Disease

For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...
GitHub

several useful jupyter notebooks from Terra - ggplot2, bulkRNAseq, ArchR, single cell with cumulus

notebooks_2020_10_08_bulk_RNAseq_pathwayAnalysis.ipynb - a bulk RNAseq analysis tutorial I wrote using kallisto quantified data (R) youtube link for a walkthrough of ...
C&EN

Toxic Switch and Key Effectors of Cu in Zebrafish Gills: Coupling Single-Cell RNA Sequencing and Redox Imaging

School of Energy and Environment and State Key Laboratory of Marine Environmental Health, City University of Hong Kong, Kowloon 999077, Hong Kong, China Research Centre for the Oceans and Human Health ...
IEEE

Knowledge-Guided Gene Panel Selection for Label-Free Single-Cell RNA-Seq Data: A Reinforcement Learning Perspective

Abstract: Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine ...