As we work on overcoming what scares us, a new plasticity becomes available in our brain, and fear strikes out.

After treatment, the mice’s memories were essentially shunted back into a younger state. The researchers found that reprogrammed engrams displayed molecular behavior of more youthful cells. Using a ...

Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common ...

A groundbreaking clinical trial is testing whether specially engineered stem cells can help the brain restore its own ...

Memories are thought to be stored in sparse groups of neurons called engrams. These are the cells that switch on during learning and can later switch on again during recall. In physiological aging and ...

A new brain implant trial aims to restore lost dopamine cells in Parkinson’s patients. Researchers are now testing it in ...

Aging doesn’t have to mean losing your past. Scientists have found a way to "reprogram" specific memory-holding neurons, restoring youthful learning and recall in mice.

For the first time ever, an anti-aging drug is providing hope for millions who suffer from this common condition.

Published in the Proceedings of the National Academy of Sciences, their study found that chronic compression triggers neuron death by a variety of mechanisms, both directly and indirectly. The ...

Brain-resident macrophages (BRMs), including microglia and border-associated macrophages (BAMs), are the core immune sentinels of the central nervous system (CNS). They originate from early embryonic ...

Isaiah Kletenik receives funding from the NIH. Nothing to disclose. Christopher M. Filley does not work for, consult, own shares in or receive funding from any company or organization that would ...

Modeling the human blood-brain barrier (BBB) is limited by the lack of robust protocols to generate induced pluripotent stem cell (iPSC)–derived brain microvascular endothelial cells (BMECs). Current ...