Promoters and enhancers: Tool catches gene-controlling DNA sequences doing each other's jobs

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...
GEN - Genetic Engineering and Biotechnology News

De-Risking RNA Therapeutics with High-Resolution Sequencing

Tina de los Reyes is the strategic biopharma development specialist for the Western US. With over 10 years of commercial experience in NGS and a Masters in Biomedical diagnostics, she specializes in ...

BioVenic Strengthens Its Position in the Rapidly Expanding Veterinary Therapeutics Research Landscape

BioVenic is dedicated to advancing the advancement of veterinary molecular diagnostics through its comprehensive ...
Medical Xpress

RNA is key to the dark matter of the genome. Scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...
Medical Xpress

Deep-learning algorithms enhance mutation detection in cancer and RNA sequencing

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...
Frontiers

Multimodal analysis of TAAD pathogenesis: SHAP-enhanced interpretable models and single-cell sequencing analysis reveal immune microenvironment alterations

Stanford type A aortic dissection (TAAD) is a fatal cardiovascular emergency with high mortality within 48 hours. Elucidating molecular mechanisms and identifying reliable biomarkers are essential for ...
News Medical

Accelerating small molecule discovery for RNA drug targets

This article and associated images are based on a poster originally authored by Adam Buckle, Julia Unsicker and Iain McWilliam and presented at ELRIG Drug Discovery 2025 in affiliation with Arrayjet ...
News Medical

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
The Scientist

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...
EurekAlert!

New review decodes transcriptomics: bulk vs. single-cell RNA sequencing

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
Barron's

Roche Sets Gene-Sequencing Record. It’s a Challenge for Illumina.

This week, the Broad Institute gene-sequencing lab said it read infants’ DNA genomes in less than four hours, cutting an hour off the previous Guinness World Record. The point for investors is that ...