A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
High-throughput sequencing, single-cell technologies, and large-scale population studies have transformed genetics and genomics into data-intensive ...
IGUA is a method for high-throughput content-agnostic identification of Gene Cluster Families (GCFs) from gene clusters of genomic and metagenomic origin. It performs three clustering iterations to ...
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