Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

A woman in her late 20s presented with a 5-year history of progressive fatigue and generalised weakness. Examination revealed signs of premature ageing, anaemia, neuropathy and hepatosplenomegaly.

Being invited to present research at an international academic conference is an honor for any seasoned professional. But for ...

While the genes involved can differ, this example illustrates how most cancers arise. Accumulated DNA mutations, acquired either over time (ageing naturally leads to some DNA mistakes) or from ...

Gene therapies have the potential to cure some diseases, but they are extraordinarily expensive. Location can also be a big ...

The Food and Drug Administration aims to evaluate treatments for rare diseases based on plausible evidence that they would work — without requiring a clinical trial first.

NSCLC remains the leading cause of cancer-related mortality worldwide, with EGFR mutations being a critical driver in approximately 10-15% of lung adenocarcinomas in Western populations, and up to 40% ...

New genome sequencing algorithm boosts human genome completeness by 20%, improving variant detection and advancing personalized medicine.

Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

An international team of scientists headed by researchers at the University of Edinburgh, has created a complete map showing how hundreds of possible mutations in a key cancer gene, CTNNB1, influence ...

Abstract: This paper presents the design and implementation of a novel matrix-friendly genetic algorithm (MGA) based population input memristor circuit. Selection, crossover and mutation operations ...