TWILIGHT adopts the progressive alignment algorithm (Fig. 1c) and employs tiling strategies to band alignments (Fig. 1e). Combined with a divide-and-conquer technique (Fig. 1a), a novel heuristic ...

Abstract: Multiple Sequence Alignment (MSA) is a fundamental challenge in bioinformatics, forming the basis for addressing numerous computational biology problems, e.g., protein structure prediction ...

Abstract: Pairwise sequence alignment of long reads is a critical step in many bioinformatics analyses. Although many pairwise sequence alignment algorithms have emerged for long-read sequencing data, ...

Sustainable Growth Advisers (SGA), an investment management company, released its fourth-quarter investor letter for its “U.S. Large Cap Growth Strategy.” A copy of the letter can be downloaded here.