News Medical

Modeling the interaction between the intestine and liver in a multi-organ microphysiological system for studying metabolic-dysfunction associated steatotic liver disease

The connection between the human liver and the intestine is unique, and the “gut-liver axis” plays a vital role in regulating liver disease pathology. When homeostasis is disturbed, changes in dietary ...
Frontiers

Molecular mechanisms and clinical studies of multi-organ dysfunction in sepsis associated with pathogenic microbial infection

Sepsis, a common complication following burns, trauma, and major surgery, remains the leading cause of death among critically ill patients. Globally, there are about 48.9 million sepsis patients and ...
Science Daily

Cell aging in one organ can snowball into multi-organ failure

The aging and failure of cells that occurs when one part of the body is damaged can spread to other organs, a study suggests. The ageing and failure of cells that occurs when one part of the body is ...
AlphaGalileo

Decoding the Sepsis Paradox: How Emergency Granulopoiesis Shifts from Defense to Dysfunction

Sepsis remains a life-threatening syndrome defined by immune dysregulation and organ dysfunction. While neutrophils act as the primary defenders of ...
EurekAlert!

Research review | Decoding the sepsis paradox: How emergency granulopoiesis shifts from defense to dysfunction

In a comprehensive review published in Research, investigators from Zhongda Hospital, School of Medicine, Southeast University propose an integrative framework centered on EG to explain this shift ...