"Monogenic" diseases, triggered by mutations in just one gene, may actually be more complex than scientists thought.

The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.

Geneticists have a better understanding of how prehistoric pairings unfolded, with new research suggesting they were mostly between male Neanderthals and female humans.

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen ...

Many psychiatric disorders are more biologically related than previously understood, having more genetic similarities than differences, a new study shows. More research is needed to understand how ...

A genetic technology known as a gene drive could help prevent malaria by spreading genes in wild mosquitoes that stop them transmitting the parasite. Tests in a lab in Tanzania have now confirmed that ...

Despite the long history of psoriasis and psoriatic arthritis (PsA), until recently, little had been known of their underlying genetics and pathogenesis. Without this knowledge, rational clinical ...

According to the study's senior author, Junghee Jenny Shin, MD, Ph.D., assistant professor of medicine (rheumatology, allergy and immunology) at YSM and director of Yale Medicine's Primary ...

In a recent study published in the journal Nature, an international team of researchers developed a novel approach to infer parent-of-origin (PofO) of alleles without parental genomes. Genome-wide ...

In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...