I'm building a custom peptide database. Rather than using conventional protein sequences, I want to search for only specific peptides. To make this compatible with standard protein-level search, I ...

I am trying to analyse DIA proteomics data using the workflow DIA_SpecLib_Quant but I am having problems with spectral library generation. When I analyse DDA data, everything goes smoothly. However, ...

Tow Center for Developmental Oncology, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, United States Computational Oncology Program, Department of Epidemiology and ...

This manuscript describes a useful integrated proteogenomics pipeline to enable the discovery of novel peptides in cancer cell lines. The method combines long-read RNA sequencing with a multi-protease ...

The rapid evolution of high-resolution mass spectrometry (MS) has necessitated the development of increasingly sophisticated proteomics software to translate complex spectral data into biologically ...