Frances Arnold's game-changing technique of "directed evolution" creates enzymes with unusual capabilities. Her own evolution made it possible.

Flame retardants, plasticizers, and "forever" chemicals are common in household items like cookware and cosmetics. But these ...

From the 1950s to 1970s, discovery of enzymes began by identifying new chemical reactions within cell-free extracts, but ...

ABSTRACT: The sugar moieties of anthocyanins can be acylated via enzymatic transesterification, which improves their solubility in lipids and enhances their stability to external factors such as light ...

Abstract: Conductometry is a widely used technique in enzyme studies as it allows researchers to monitor the activity of enzymes in solution. The determination of enzymatic activity, a time-dependent ...

The manuscript by Mancl et al. provides important mechanistic insights into the conformational dynamics of Insulin Degrading Enzyme (IDE), a zinc metalloprotease involved in the clearance of amyloid ...

Metabolite-mediated feedback represents a rather unexplored mode of metabolic regulation in plants and other organisms. This study identifies methylerythritol cyclodiphosphate (MEcPP), an intermediate ...

We found that β-1, 4-glucosidase, β-D-cellobiosidase, β-1, 4-N-acetylglucosaminidase, and L-leucine aminopeptidase in SOCE and MBCE, the soil enzyme activity coefficient (SEAC), and the geometric mean ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Directed evolution offers a complementary strategy by ...

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