KLF5 appears to fuel pancreatic cancer metastasis by reprogramming epigenetic controls, offering a potential new therapeutic target.

In our cells, our DNA carries chemical or 'epigenetic' marks that decide how genes will be used in different tissues. Yet in the group of specialised ...

In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...

Resistant cells demonstrated global decreases in DNA accessibility with localized opening at resistance-driving loci, ...

British scientist says humans could live 20,000 years through DNA reprogramming and cellular repair technology that eliminates aging.

Since the dawn of the computer age, researchers have wrestled with two persistent challenges: how to store ever-increasing reams of data and how to protect that information from unintended access. Now ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

ABSTRACT: Epigenetic mechanisms regulate and stabilize a broad range of biological processes without altering the primary DNA sequence. This regulation is achieved through DNA methylation, ...

Medical scientist Eduardo Marbán – then at Johns Hopkins and now Cedars-Sinai – found that heart progenitor cells also have a special mechanism where they send out sacs, known as exosomes, which carry ...

Besides convenience, one of the main benefits of self-driving cars is supposed to be safety. Yet in a bizarre move, Waymo — whose self-driving cabs had been enjoying extraordinary safety metrics — has ...

Viral infection profoundly reprograms host glucose metabolism to support replication. This review proposes a “Sprint vs. Marathon” framework to explain how viral life cycles shape distinct metabolic ...