Open Heart

Enhanced cardiovascular disease risk prediction using integrated machine learning models: a study from the UK Biobank cohort

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...
Greek Reporter

The Scholars Who Deciphered the Ancient Greek Script Linear B

If not for the work of two scholars, Alice Kober and Michael Ventris, the ancient Greek script Linear B would likely still be ...
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...
AHA/ASA Journals

HEV-Targeted Antibody-Drug Conjugate Promotes Long-Term Cardiac Allograft Acceptance

BACKGROUND: The entrance of naive T cells into lymph nodes (LNs) is a crucial step for induction of heart transplant acceptance under costimulatory blockade. Specialized blood vessels within the LN ...

Calculate Fixed Asset Depreciation in Excel: A Guide

Learn to calculate fixed asset depreciation in Excel using methods like straight-line, sum of the years' digits, and more for accurate financial analysis.
BMJ Open

Association between maternal age at childbirth and children’s internalising problems in the USA: a cross-sectional mediation analysis of housing instability and family ...

Objectives The optimal maternal age at childbirth has been a topic of bourgeoning literature, with earlier ages offering physiological benefits for maternal recovery. In contrast, later ages to give ...