Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Six of these molecules were found to be more accurate at predicting two-year survival than things like age and cholesterol levels.

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a ...

As people age, it becomes harder to know who is on track for healthy years ahead and who may be at higher risk for serious ...

People who lived longer had lower piRNA levels, suggesting these molecules may play a direct role in how long we live.

More than 300,000 people suffer a heart attack in Germany every year. The heart muscle is then no longer supplied with sufficient blood and oxygen, and part of the tissue dies and scars. Unlike the ...

Discover how an ancient gene influences the sex of ant, bee, and wasp embryos, impacting conservation and breeding practices.

New techniques to detect Y chromosome genes show frequent loss of the Y in tissues of older men. The increase with age is clear: 40% of 60-year-old men show loss of Y, but 57% of 90-year-olds.

Genetic studies now identify millions of variants across human populations, yet most disease-associated signals fall outside protein-coding regions. This ...

Key opportunities in the pancreatic cancer market include advancing novel therapies such as masitinib, pamrevlumab, and quemliclustat, alongside strategic collaborations and FDA designations to foster ...

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.