A team led by researchers at the University of Cologne has identified a protein called ANKIB1 that acts as a volume dial for the body’s frontline immune defenses, controlling how strongly cells ...

A newly discovered biological chain reaction explains how high levels of a common brain chemical can lead to cellular ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

CD25 rewires oncogene signaling in AML and ALL, revealing druggable complexes and a bold strategy: push pathways into toxic ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Researchers have discovered a previously unknown signalling cascade that determines how powerful our innate immune system responds to virus infections. This discovery has broad implications for ...

A hidden molecular chain reaction in the brain may push key cellular systems into overdrive in autism—and scientists just found a way to switch it off.

About one in eight U.S. adults are currently taking a GLP-1 drug such as Ozempic, Wegovy, or Zepbound to treat diabetes, ...

Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells ...

The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form highly organized clusters with cell surface RNA binding proteins (csRBPs), ...

This important work combines theoretical analysis with precise experimental perturbation to demonstrate a previously unappreciated quantitative characteristic of the Wnt signaling pathway, which is ...