An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox ...

The results of a randomized controlled trial (RCT) indicate that meningococcal B vaccine is not effective at preventing ...

Orforglipron, a novel oral nonpeptide GLP-1 receptor agonist (RA), led to a greater reduction in A1c and more significant weight loss compared to oral semaglutide in patients with type 2 diabetes (T2D ...

Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic ...

Racial disparities on incidence and survival in Kaposi sarcoma during the post-retroviral era: A Surveillance, Epidemiology and End Results program database (2000-2021) retrospective analysis. This is ...

Pivotal study shows no clear benefit for the common endoscopic procedure in this patient group. Experts say the new data ...

A randomized trial of hospitalized patients with moderate hyponatremia compared targeted sodium correction versus routine care on mortality and rehospitalization rates.

‘A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial’ by David Erritzoe et al. was published in Nature Medicine at 16:00 UK time on ...

Hand-foot syndrome (HFS) is a dose-limiting side effect of capecitabine. Celecoxib prevents HFS by inhibiting cyclooxygenase-2 (COX-2) that is upregulated because of the underlying associated ...

A 20-year follow-up of older adults in the ACTIVE randomized trial linked to Medicare claims found that speed of processing cognitive training with booster sessions was associated with a significantly ...