Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

According to this model, sigma (σ) factors bind to RNA polymerase to initiate transcription—the process by which genetic information is copied from DNA to RNA—and then detach after initiation to allow ...

IGF2BP2 binds to a number of RNA transcripts and has been suggested to function as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism. Here ...

By Hugo Francisco de Souza Emerging research suggests reversible RNA editing mechanisms may influence heart disease biology while opening new avenues for biomarkers and next-generation cardiovascular ...

Researchers discover that the RNA surveillance system NMD and the protein UPF2 are essential for guiding neuronal migration and forming the brain's layered cortex.

Researchers at the Icahn School of Medicine at Mount Sinai say they have made a new discovery about how human cells make RNA, a molecule that functions as a set of blueprints that tell cells how to ...

Dr. Anczukow is a leading cancer biologist with expertise in RNA biology, molecular and cell biology, as well as human genetics, cancer biology, and genomics Olga Anczukow, Ph.D. Olga Anczukow, Ph.D.