Figure 1: Mouse TIM does not inhibit CLOCK/MOP4:BMAL1-mediated transcription in S2 cells. To delineate potential functions of mTim, we disrupted the gene by targeted mutagenesis. A targeting vector ...
The APOE3 Targeted Replacement model is one line in a set of three APOE knock-in lines created by Nobuyo Maeda, Patrick Sullivan, and colleagues. APOE2 and APOE4 Targeted Replacement mice are also ...