Devdiscourse

When Algorithms Meet Biology: Testing AI Agents in Real-World DNA Workflows

A RAND study found that the newest AI models can design lab-ready DNA sequences and generate workable protocols, successfully ...
Open Heart

Enhanced cardiovascular disease risk prediction using integrated machine learning models: a study from the UK Biobank cohort

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...

Big data and human height: Scientists develop algorithm to boost biobank data retrieval and analysis

Extracting and analyzing relevant medical information from large-scale databases such as biobanks poses considerable challenges. To exploit such "big data," attempts have focused on large sampling ...

Expands the genetic alphabet: Artificial DNA base pair uses halogen bonds to form stable structures

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different ...
Nature

Personalized mRNA vaccine induces strong, durable immunity in hard-to-treat breast cancer

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...
eLife

Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...
eLife

Adaptation of an herbivorous arthropod to green tea plants by overcoming catechin defenses

Department of Chemistry and Biochemistry, University of South Carolina, Columbia, United States ...