p-values are commonly used as summaries of evidence for association between a genetic variant and phenotype, but they have an important limitation in that they are unable to quantify how confident one ...

This study uses a Bayesian framework to characterize latent brain state dynamics associated with memory encoding and performance in children, as measured with functional magnetic resonance imaging.

Anticoagulation is a critical component in the treatment of cardiovascular diseases. Large randomised controlled trials have ...

Introduction Cerebral palsy (CP) is a non-progressive condition involving movement and muscle tone difficulties due to injury to the developing brain. Most cases arise around birth, but a smaller ...

Pew Research Center is a nonpartisan, nonadvocacy fact tank that informs the public about the issues, attitudes and trends shaping the world.

As social media becomes the core domain of information interaction in the era of big data, the emotional information contained in the vast amount of user-generated content provides an unprecedented ...

Objectives Studies on ageing trajectories typically foreground intrinsic capacities and focus on frailty and mortality outcomes. Instead, research capturing aspects of people’s living environment ...