As rare disease trials face persistent feasibility challenges, Bayesian designs are gaining momentum by enabling more ...

The FDA has released draft guidance on how sponsors can use Bayesian models for clinical trials.

Marty Makary was appointed commissioner of the Food and Drug Administration (FDA) in 2025. The prominent surgeon, medical researcher, bestselling author, and critic of the medical ...

This study provides a useful contribution to understanding how wearable augmentation devices interact with human proprioception, using a longitudinal design over a single session. Results demonstrate ...

Objectives Studies on ageing trajectories typically foreground intrinsic capacities and focus on frailty and mortality outcomes. Instead, research capturing aspects of people’s living environment ...

As social media becomes the core domain of information interaction in the era of big data, the emotional information contained in the vast amount of user-generated content provides an unprecedented ...

p-values are commonly used as summaries of evidence for association between a genetic variant and phenotype, but they have an important limitation in that they are unable to quantify how confident one ...

Introduction Cerebral palsy (CP) is a non-progressive condition involving movement and muscle tone difficulties due to injury to the developing brain. Most cases arise around birth, but a smaller ...

The US equity market stands at the most extreme valuations in history, on the measures we find best correlated with actual ...