Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

A tumor “don’t‑eat‑me” shield also hides pro‑immune danger signals; new antibodies that unmask this hidden cue could make cancers more vulnerable to immune attack.

Restoring the gut microbiota through fecal microbiota transplantation reversed these effects. The treatment replenished CX3CR1-positive NK cells, reduced lung damage, and improved survival. Targeted ...

CAMBRIDGE, MA -- By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers have found a way to force tumors to trigger their own ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching effects regarding immune responses, inflammatory processes, and diseases. A ...

Researchers have revealed how a common bacterium, Enterococcus faecalis (E. faecalis), releases lactic acid to acidify its ...

Researchers at UAB have identified an immune pathway that might help explain why some women develop a serious pregnancy ...

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous ...