Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...
Learn how modified fluorescent proteins are evolving into quantum sensors, enhancing our understanding of cellular processes.
CAMBRIDGE, MA – A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer’s, cystic fibrosis, and cancer. But there are about 70,000 different proteins and ...
An international team has assembled the first large-scale, publicly available map to show the impact of mutations on where proteins end up in the cell. The team developed a high-throughput imaging ...
The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to ...
This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...
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The life cycle of a protein

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...
Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...