Podocytes respond to hormones and growth factors that are present in the circulation or locally produced in the glomerulus A variety of receptors on the cell surface are thought to enable podocytes to ...

Unlike other human stem cells, Induced pluripotent stem cells (iPS cells) can be produced directly from adult cells. Now, researchers have shown that human kidney podocytes produced from iPS cells via ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

A single podocyte was reconstructed in three dimensions based on serial glomerular section images obtained by array tomography. The three-dimensional reconstruction enabled quantitative volume ...

Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

A newly-established protocol offers hope for kidney disease modeling, drug discovery, and potential cell therapies. Previous work from the Wyss Institute at Harvard University established a protocol ...

Senior Postdoctoral Research Fellow, GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology, Children's Hospital Los Angeles The glomerular filtration barrier, generated ...

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the ...

As one of the major targets of Covid-19, infection in the kidneys can led to significant complications associated with kidney disease, as well as kidney failure. Kidney damage can occur even in those ...

Kidney complications are some of the most common and severe symptoms associated with Covid-19. Estimates show that 30% of people hospitalized for severe infection and 50% of those that are later ...