The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Quantitative phase imaging is a powerful, non-invasive and quantitative microscopy technique that allows multi-scale imaging of cellular systems, explain Mustafa Mir and Gabriel Popescu Imaging by ...

The use of high-resolution bright-field microscopy is essential for cellular-scale biological research, but this technique has limitations due to low image contrast. Using dyes on the sample can ...

With conventional biological microscopes, special tools are needed for adjusting the components required for phase contrast observation. With the SI-PH Phase Condenser, centering of the ring aperture, ...

Integrating deep learning in optical microscopy enhances image analysis, overcoming traditional limitations and improving classification and segmentation tasks.

Ptychography is an area-by-area scanning method that uses constant, coherent illumination to scan a region of a sample in several adjacent and overlapping locations. The dispersed radiation is ...