Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator ...
Global proteomics and functional analyses reveal that p53-induced ZMAT3 suppresses mitochondrial respiration by inhibiting transcription of a hexokinase, uncovering a role for ZMAT3 in transcription.
Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney Kimmel ...
The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the ...
Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or ...
A research team at the University of Konstanz, led by toxicologist Ivano Amelio, has demonstrated how differently individual mutations of the tumor suppressor p53 affect pancreatic carcinomas. When ...
Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study, published in ...
Add Yahoo as a preferred source to see more of our stories on Google. Cancer Cell Spread and oncology or Malignant Cancerous Growth and Metastasis anatomy concept as growing tumor cells and Malignancy ...
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