Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.
The human NPC is composed of approximately 34 nucleoporin proteins. The interior, or “symmetric,” core is composed of an inner ring, and two outer rings that sit on either side of the nuclear envelope ...
In situ model of the nuclear pore complex transport barrier: Tethered within the pore are highly dynamic protein threads termed FG Nups (green). Under physiological conditions, cargo-carrying ...
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