TMCnet

Data Normalization vs. Standardization: What's the Difference and When to Use Each

Data Normalization vs. Standardization is one of the most foundational yet often misunderstood topics in machine learning and ...
Nature

SCnorm: robust normalization of single-cell RNA-seq data

The normalization of RNA-seq data is essential for accurate downstream inference, but the assumptions upon which most normalization methods are based are not applicable in the single-cell setting.
Nature

Normalization of RNA-seq data using factor analysis of control genes or samples

Normalization of RNA-sequencing (RNA-seq) data has proven essential to ensure accurate inference of expression levels. Here, we show that usual normalization approaches mostly account for sequencing ...
ascopubs.org

Statistical Assessment of Depth Normalization for Small RNA Sequencing

We collected a unique pair of microRNA sequencing data sets for the same set of tumor samples; one data set was collected with and the other without uniform handling and balanced design. The former ...