Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant ...

Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage phagosomes. The ...

Parkinson’s disease may begin reshaping the body’s chemistry years before the first tremor or stiffness appears. A growing ...

A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development ...

Obesity and type 2 diabetes affect hundreds of millions of people worldwide and are key drivers of MASH, now the fastest-growing cause of advanced liver disease, liver cancer, and transplantation.

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...