Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving ...

A non-intoxicating compound in cannabis could offer a breakthrough treatment for alcohol use disorder. New research shows CBD ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Your endless scroll may be costing you more than just your time. New research shows it’s changing the way you think and make decisions. These days, almost everything is available in the form of quick, ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

Is Internet Addiction Disorder (IAD) real? A new study suggests it may be — and that its effects can be seen in the human brain. The study asked those between the ages 14 and 21 questions about how ...