Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

These resources provide an overview to how the basic principles of inheritance were studied and elucidated by Gregor Mendel. Basic linkage analysis is also described to serve as a foundation for more ...

Genetic testing can confirm a muscular dystrophy (MD) diagnosis when symptoms and other tests already suggest MD. It also identifies specific gene mutations that can guide targeted treatment. Genetic ...

How much of our lifespan is written in our genes, and how much is sitting on our plates? A new analysis suggests that while ...

Princeton University scientists have developed a new way to identify the hidden genetic material responsible for complex traits, a breakthrough they believe ultimately could lead to a deeper ...

Duchenne muscular dystrophy (DMD) is a genetic condition that primarily affects people assigned male at birth. However, due to the condition’s X-linked inheritance pattern, only people assigned female ...

The Finnish population has provided investigators with a rare opportunity. Most Finns descend from a small, so-called founder population of individuals, and people have primarily reproduced with ...

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex Phillippidis, ...