Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

A cell-free genomics approach silences cellular noise and reveals transcription drivers, improving our understanding of a ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

New research links Wnt signalling to aggressive paediatric liver cancer and chemoresistance. Learn what this means for treatment.

New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Studying gene expression in a cancer patient's cells can help clinical biologists understand the cancer's origin and predict ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...