Dissolution testing plays an important role throughout the life cycle of a pharmaceutical product, i.e., from evaluating how quickly a compound dissolves into solution in controlled conditions to ...
In the manufacture of solid dosage forms, the rate at which the active pharmaceutical ingredient (API) is dissolved into solvents simulating the digestive tract fluids is determined with dissolution ...
Despite its importance in drug development, dissolution testing still has some limitations, but advances in automation and real-time monitoring are producing promising results. The importance and ...
A fully automated dissolution lab is an integrated, end to end architecture that enables reproducible testing, continuous ...
an active pharmaceutical ingredient is the active ingredient contained in a drug and it is the basic material with the desired pharmaceutical properties. Active pharmaceutical ingredients play core ...
Dissolution and drug release tests are directly relevant to the safety and efficacy of many common pharmaceutical dosage forms. To achieve reliable and reproducible results, it is important that ...
This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing. A ...
Mark Hammond, Business Development Manager of Melbourn Scientific has explained that a large number of the more recent active ingredients are poorly soluble in traditional media and expose the ...