An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has introduced CGSchNet, a machine-learned coarse-grained (CG) model that can ...

John Jumper (S.M. ’12, Ph.D. ’17) was awarded the Nobel Prize in Chemistry in 2024 for his contributions to the development of AlphaFold, an AI model that revolutionized protein structure prediction.

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin introduces a breakthrough in protein simulation. The study, published in the ...

CGSchNet, a fast machine-learned model, simulates proteins with high accuracy, enabling drug discovery and protein engineering for cancer treatment. Operating significantly faster than traditional all ...

In the field of protein biochemistry, the emergence of nonaqueous solvents such as ionic liquids (ILs) and deep eutectic solvents (DES) has unveiled new ...

Membrane proteins constitute a significant fraction of cellular proteomes and play indispensable roles in signalling, transport, and metabolism. Their folding and subsequent stability are not only ...

Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint, the genetic information. Here, the basic building blocks of proteins, ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...