A long-standing challenge to evolutionary theory has been whether it can explain the origin of complex organismal features. We examined this issue using digital organisms—computer programs that ...
The nucleosome remodelling and histone deacetylase (NuRD; also known as Mi-2) complex is a multisubunit chromatin remodelling complex that contains two core subunits (chromodomain-helicase-DNA-binding ...
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe.
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