Complement Factor H (CFH) is a pivotal regulator of the complement system, integral to maintaining immune homeostasis and protecting host tissues from undue complement‐mediated damage. By inhibiting ...

RGC-32, or Response Gene to Complement 32, plays a pivotal role in mediating cellular responses following complement activation. Acting as a regulator of the cell cycle, RGC-32 is implicated in ...

Northwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to ...

The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and autoimmune conditions when it turns against the body. The protein, Granzyme K, ...

For years, patients with C3G and IC-MPGN had few options to stop the progression toward kidney failure. Now a new class of ...

Skin, our largest organ, acts as a protective barrier against pathogens that try to invade our bodies while constantly ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Sepsis is globally recognized as a primary contributor to morbidity and mortality. The Sepsis 3.0 definition is captured as ...

Montgomery Andresen joins from T-Cypher Bio; Follows breakthrough non-human primate data demonstrating deep B-cell depletion without cytokine release; Commit is p ...