Figure 2: FRQ activities in circadian feedback loops are impaired in the frq codon-optimized strains. Figure 3: FRQ protein in the codon-optimized strains is less stable and more sensitive to trypsin ...
Morning Overview on MSN
AI model cracks yeast DNA code to turbocharge protein drug output
MIT researchers have built an AI language model that learns the internal coding patterns of a yeast species widely used to manufacture protein-based drugs, then rewrites gene sequences to push protein ...
The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...
Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful ...
Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
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