New Assay Expands INDIGO’s GPCR Portfolio and Supports Development of Next-Generation CNS-Related Therapeutics STATE ...
Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD and chemical imbalances.
Morning Overview on MSN
Study: Acetylcholine can take over serotonin release in key brain circuit
Researchers have identified a mechanism by which acetylcholine, a neurotransmitter best known for its role in muscle control and attention, can effectively commandeer serotonin release inside the ...
Due, in part, to the logical nature of the approach, combination therapy is already widely used in clinical practice. Although compounds with a combined cholinergic–glutamatergic action have been ...
Kaiser Permanente Washington scientists report that higher cumulative anticholinergic exposure predicted a faster decline in gait speed and grip strength among older adults. Inappropriate polypharmacy ...
Pharmaceutical Technology on MSN
Vima banks $100m in Series A to progress Parkinson’s drug
The selective muscarinic agonist is now in mid-stage development for movement disorders like Parkinson’s disease and dystonia.
Expert Rev Neurother. 2012;12(11):1351-1365. With regard to understanding the disease process in AD, it is of considerable interest to consider the temporal relationship between the loss of ...
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