The GPR133 receptor is expressed by osteoblasts, the cells that make bone. The study suggests that this receptor helps those cells sense two kinds of input: mechanical strain and signals relayed by ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...

Dublin, OH / Syndication Cloud / March 15, 2026 / SPRY 365 The Postmenopausal Bone Loss Crisis Every year after ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the skeleton are often overlooked. Excess body fat can disrupt bone metabolism, ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from the Institute of Science Tokyo, Japan. Hypoxic conditions ...

A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Adolescents with overweight or impaired glucose ...

Doctors say bone loss can begin silently in the early 30s, especially in women. Hormonal changes, sedentary lifestyles, low sunlight exposure, and poor nutrition may accelerate the process. Because ...