A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

Scientists may have figured out a brand new way to treat lung cancer by using a protein that inhibits tumor growth. This previously unknown molecule pathway could help researchers develop personalized ...

Designing proteins that can change their structure, and ultimately function, in response to specific molecular signals, a phenomenon known as allosteric regulation, has been a long-standing goal of ...

Amyloids are perhaps best known as a key driver of Alzheimer’s disease. The amorphous proteins, found throughout the human body, stick to nerve cells like plaque, choking off their function and ...

Researchers are testing a fundamentally different strategy against neurodegenerative disease: instead of clearing protein deposits after they form, new experimental therapies aim to stop toxic protein ...