Archaeal DNA replication combines features of bacterial and eukaryotic systems within a unique framework adapted to extreme environments and diverse genome architectures. Initiation typically occurs ...
Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...
An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived ...
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