DNA is the chemical that codes for proteins which determine our physical traits. This molecule is a double coil connected by cross pieces (called bases). There are four bases that can vary in sequence ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...

In 2018, Dr. Claudia Gonzaga-Jáuregui, who years before had completed her doctorate studies in Dr. James R. Lupski's lab at Baylor College of Medicine, received an email from an editor at Elsevier's ...

Daphne O. Martschenko and Sam Trejo both want to make the world a better, fairer, more equitable place. But they disagree on whether studying social genomics—elucidating any potential genetic ...

Hereditary cancer is caused by germline mutations, typically following an inheritance pattern within a family. In contrast, sporadic cancer is caused by somatic mutations interacting with ...

Genetic testing identifies germline mutations, while genomic testing analyzes somatic mutations in tumors, influencing treatment options. Broader testing criteria are expanding access to genetic ...

The team, composed of Scripps Research Professor Nicholas Schork, a genomics researcher and director of biostatistics and bioinformatics with Scripps Translational Science Institute (a collaboration ...

Diabetes is a complex condition. It has several forms and can affect multiple organs, causing various other diseases and long-term health issues. For instance, clinical evidence shows that eye damage ...

As a teenager just moved to Iowa from war-ravaged Germany in 1951, John M. Opitz, M.D., wanted to study developmental biology, but his “very Prussian” mother insisted he go to medical school instead.