BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Aortic stenosis is a disease often diagnosed in its asymptomatic phase due to its distinct murmur and the widespread use of noninvasive imaging. The history, however, is still of paramount importance ...

(CHICAGO) –Bone-like cells similar to the cells found in the skeleton calcify in the heart's aortic valve and are responsible for the blockages that lead to the need for open-heart surgery to replace ...

Please provide your email address to receive an email when new articles are posted on . “These data from a large, 5-year, randomized, double-blind, placebo controlled trial of older women did not ...

Mechanisms of heart-valve disease often mimic processes observed in embryonic and early childhood development, including activation of valvular interstitial cell (VIC) phenotypes and remodeling of ...

Recent research from Karl Landsteiner University of Health Sciences (KL Krems) provides important new insights into how ...

Computed tomography (CT)-based measures of calcification in the abdominal aorta are strong predictors of heart attacks and other adverse cardiovascular events—stronger even than the widely used ...

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Please provide your email address to receive an email when new articles are posted on . Older patients and those with chronic kidney disease who have abdominal aortic calcification are at elevated ...