Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

The impact of addiction on the brain is both catastrophic and comprehensive. When the brain is damaged by an addicting chemical, its executive functions—including judgment, decision making, and ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one ...

GLP-1 medications may quiet the brain signals behind addiction, reducing substance use disorders and overdose risk across ...

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge. The study, published today in ...

Drugs originally designed to treat diabetes and obesity are reshaping medicine in unforeseen ways. Their impact on public health is really unprecedented in modern times, perhaps only upstaged by ...

This post is in response to Does My Binge Drinking Mean I’m an Alcoholic? By Lantie Elisabeth Jorandby M.D. Most people who drink alcohol do so socially and in moderation. But for some, alcohol ...